MXiPr (Methoxisopropamine): Comprehensive Overview and Research Applications

MXiPr (Methoxisopropamine) is a novel research chemical belonging to the arylcyclohexylamine class, a family of compounds structurally related to dissociative substances such as ketamine and PCP analogs. As a relatively new entrant to the field of chemical and pharmacological research, MXiPr has gained growing attention for its potential to deepen scientific understanding of NMDA receptor antagonism, neurological pathways, and psychoactive compound pharmacodynamics.

This compound is available strictly for laboratory and analytical research purposes only. It is not intended for human or veterinary use.

Chemical Profile of MXiPr (Methoxisopropamine)

• Chemical Name: 2-(3-Methoxyphenyl)-2-(isopropylamino)cyclohexanone

• Common Name: MXiPr

• IUPAC Name: (±)-2-(isopropylamino)-2-(3-methoxyphenyl)cyclohexanone

• Chemical Class: Arylcyclohexylamine

• Molecular Formula: C16H25NO2

• Molecular Weight: 263.38 g/mol

• Form: Typically supplied as a crystalline powder or fine solid

• Purity: ≥98% (laboratory-grade standard)

As part of the MX-series compounds (which includes MXE, MXPr, and MXiP), MXiPr features subtle structural modifications that provide unique opportunities for structure–activity relationship (SAR) studies. The presence of an isopropylamino substitution gives it distinct chemical and physical properties, making it a compound of interest for comparative neurochemical research.

Pharmacological Background and Research Significance

MXiPr (Methoxisopropamine)  is primarily investigated for its NMDA receptor antagonist activity. NMDA receptors are a subtype of glutamate receptors involved in synaptic plasticity, memory formation, and neuroprotection. Compounds that modulate these receptors are central to understanding neurological and psychiatric conditions such as depression, schizophrenia, and neurodegenerative disorders.

Preliminary laboratory research on structurally related compounds (such as MXE and MXPr) has shown that NMDA receptor antagonists can influence glutamatergic signaling, dopamine transmission, and cortical connectivity. As a close analog, MXiPr (Methoxisopropamine) provides valuable insight into how small molecular substitutions can alter binding affinity, receptor selectivity, and metabolic pathways.

Scientists and researchers are increasingly exploring MXiPr (Methoxisopropamine) for:

• Receptor Binding Studies: Investigating NMDA receptor interactions and antagonistic profiles.

• Comparative Pharmacology: Assessing how the isopropyl group impacts receptor affinity versus other alkyl substitutions.

• Neurotoxicity and Safety Profiling: Examining potential neuroprotective or excitotoxic properties.

• Analytical Chemistry Research: Developing advanced detection methods (GC-MS, LC-MS, and NMR analysis).

Physical and Chemical Properties

MXiPr’s crystalline structure and solubility profile make it suitable for solution preparation, spectroscopic analysis, and instrument calibration. It exhibits moderate lipophilicity, allowing it to serve as a model for studying blood-brain barrier permeability in synthetic analogs.

Common laboratory properties include:

• Appearance: Off-white crystalline or powder form

• Solubility: Soluble in ethanol, DMSO, and other organic solvents

• Melting Point: Data under investigation

• Storage Conditions: Store in a cool, dry environment away from light and moisture

Proper laboratory handling procedures should always be observed, including the use of gloves, protective eyewear, and fume hoods to prevent accidental exposure.

Legal Status and Compliance

As of the latest available information, MXiPr is an unscheduled research chemical in many jurisdictions. However, legal regulations surrounding novel psychoactive substances (NPS) vary by region and are subject to rapid change. Researchers are responsible for ensuring that possession and use of MXiPr (Methoxisopropamine) comply with all local, state, and federal laws before ordering or conducting experiments.

This product is supplied exclusively for scientific and forensic research. It is not approved for medical, veterinary, or human consumption under any circumstances.

Why Researchers Choose MXiPr (Methoxisopropamine)

MXiPr has become a compound of interest among researchers due to several key factors:

1. Structural Novelty: The isopropylamino substitution provides a new framework for studying NMDA receptor activity.

2. Analytical Versatility: Ideal for GC-MS and HPLC calibration, receptor-binding assays, and comparative analysis.

3. High Purity Assurance: Laboratory-grade synthesis ensures consistent and reproducible results.

4. Contribution to Modern Neuroscience: MXiPr supports ongoing academic efforts to understand dissociative mechanisms and neurotransmission pathways.

Safety and Handling Guidelines

When working with MXiPr, follow standard laboratory safety protocols:

• Handle only in a controlled laboratory setting.

• Use appropriate PPE (personal protective equipment) including gloves, lab coat, and respirator mask if necessary.

• Avoid inhalation, ingestion, or skin contact.

• Dispose of all waste material in accordance with institutional and environmental guidelines.

Safety Data Sheets (SDS) and analytical certificates are typically available upon request to ensure compliance with research standards.

Conclusion: The Future of MXiPr Research

MXiPr (Methoxisopropamine) represents a promising frontier in neuropharmacological and chemical research, bridging the gap between established NMDA receptor antagonists and next-generation dissociative analogs. Its distinctive molecular structure allows researchers to explore novel aspects of receptor interaction, structural binding efficiency, and neurochemical modulation.

As interest in the MX-series continues to evolve, MXiPr (Methoxisopropamine) stands out as a compound that expands scientific understanding while underscoring the importance of safe, ethical, and legally compliant research practices.