4-HO-DET

4-HO-DET: A Comprehensive Overview of the Synthetic Psychedelic Compound

Introduction of 4-HO-DET

4-Hydroxy-N,N-diethyltryptamine (4-HO-DET), also known as ethocin or CZ-74, is a synthetic psychedelic compound belonging to the tryptamine class. It is structurally related to psilocin, the active compound in “magic mushrooms,” and shares similar psychoactive properties. First synthesized in the 1960s by Albert Hofmann and Franz Troxler at Sandoz Laboratories, 4-HO-DET has been the subject of scientific research and anecdotal reports due to its unique effects and potential applications in psychedelic therapy.

Chemical Structure and Properties 4-HO-DET

The chemical formula of 4-Hydroxy-N,N-diethyltryptamine is C14H20N2O, with a molecular weight of approximately 232.32 g/mol. Its structure comprises an indole ring system substituted with a hydroxyl group at the 4-position and an ethyl group at the nitrogen atom. This configuration classifies it as a substituted tryptamine, akin to other psychedelics like psilocin and 4-HO-DMT. The compound is typically encountered as a white crystalline powder or in its fumarate salt form PubChem+1.

Mechanism of Action 4-HO-DET

4-Hydroxy-N,N-diethyltryptamine exerts its effects primarily through serotonin receptor agonism, particularly at the 5-HT2A receptor. This interaction leads to alterations in perception, mood, and cognition. As a non-selective serotonin receptor agonist, it also interacts with other serotonin receptors, contributing to its complex psychoactive profile. The compound’s effects are comparable to those of psilocin, though individual experiences may vary Wikipedia.

Dosage and Duration

The typical oral dosage of 4-Hydroxy-N,N-diethyltryptamine ranges from 10 to 25 mg, with effects usually onset within 30 to 45 minutes. The duration of action spans approximately 2 to 6 hours, depending on the dose and individual metabolism. Users have reported that the experience is often shorter and more manageable compared to substances like LSD, making it appealing for those seeking a brief psychedelic experience acslab.com.

Effects Profile 4-HO-DET

The effects of 4-HO-DET are similar to those of other tryptamine psychedelics, including:

• Visuals: Enhanced colors, geometric patterns, and visual distortions.

• Cognitive Effects: Altered thought processes, introspection, and philosophical insights.

• Emotional Effects: Elevated mood, increased empathy, and a sense of connectedness.

• Physical Sensations: Possible mild stimulation or body load.

Some users have reported experiences of ego dissolution or encounters with non-human entities, though these effects are less commonly associated with 4-HO-DET compared to other psychedelics like DMT wiki.dmt-nexus.me.

Safety and Side Effects 4-HO-DET

The safety profile of 4-Hydroxy-N,N-diethyltryptamine is not well-documented due to the lack of extensive clinical studies. However, anecdotal reports suggest that, when used responsibly, it has a relatively mild side effect profile. Potential adverse effects may include anxiety, dizziness, or nausea, particularly at higher doses CBD Nationwide.

Legal Status

The legal status of 4-HO-DET varies by jurisdiction. In some countries, it may be classified as a controlled substance, while in others, it may not be explicitly regulated. Individuals interested in the legal status of 4-Hydroxy-N,N-diethyltryptamine in their region should consult local laws and regulations.

Conclusion

4-Hydroxy-N,N-diethyltryptamine is a synthetic psychedelic compound with a chemical structure and effects profile similar to psilocin. While it has not been extensively studied in clinical settings, anecdotal reports suggest that it offers a unique and manageable psychedelic experience. As with any psychoactive substance, responsible use and adherence to legal guidelines are paramount. Further research is needed to fully understand the therapeutic potential and safety profile of 4-HO-DET.